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Related Experiment Video

Updated: Jan 26, 2026

Individualized Reconstitution of Human Milk Microbiota: A Feasible Approach in Real-World Settings
04:16

Individualized Reconstitution of Human Milk Microbiota: A Feasible Approach in Real-World Settings

Published on: February 7, 2025

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Balancing access to donor human milk: Rationing vs expanding use.

Ting Ting Fu1, Stephanie Merlino-Barr2, Melina Roy2

  • 1Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition
|January 25, 2026
PubMed
Summary

Pasteurized donor human milk (DHM) is a key alternative to mother's own milk (MOM) for infants. While beneficial for high-risk preterm infants, its superiority over infant formula for other populations requires further investigation.

Keywords:
breast milkdonor human milkdonor milk bankhealthcare rationinghuman milk

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Area of Science:

  • Neonatal Nutrition
  • Infant Feeding Practices
  • Human Milk Research

Background:

  • Mother's own milk (MOM) is the optimal nutrition for infants.
  • Pasteurized donor human milk (DHM) is the preferred alternative when MOM is unavailable.
  • DHM offers unique benefits compared to infant formulas, though not identical to MOM.

Purpose of the Study:

  • To review the evidence for donor human milk (DHM) use in various infant populations.
  • To discuss the potential benefits and limitations of expanded DHM utilization.
  • To explore controversies and barriers affecting DHM access and distribution.

Main Methods:

  • Literature review and synthesis of existing evidence on DHM.
  • Analysis of clinical outcomes associated with DHM versus infant formula.
  • Examination of regulatory, financial, and logistical factors influencing DHM availability.

Main Results:

  • Strong evidence supports DHM for high-risk preterm and very low birth weight infants.
  • The superiority of DHM over infant formula for other infant groups is less established.
  • Expanded DHM use is observed in infants with specific medical conditions, but inconsistently.

Conclusions:

  • DHM is a valuable nutritional option, particularly for vulnerable preterm infants.
  • Further research is needed to clarify DHM's clinical benefits over infant formula in diverse infant populations.
  • Addressing barriers to DHM access is crucial for equitable infant nutrition.