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Biliary Embryonal Rhabdomyosarcoma: A Case Report.

M M Chowdhury1, M M Warid, S Mohammed

  • 1Professor Dr Md Mohsen Chowdhury, Professor & Chairman, Hepatobiliary, Pancreatic and Liver Transplant Surgery Department, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh;

Mymensingh Medical Journal : MMJ
|July 1, 2023
PubMed
Summary
This summary is machine-generated.

A rare embryonal rhabdomyosarcoma in the common bile duct (CBD) was successfully treated in a 10-year-old boy. This pediatric cancer required surgery, chemotherapy, and T-tube placement for recovery.

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Area of Science:

  • Pediatric oncology
  • Surgical gastroenterology
  • Rare pediatric tumors

Background:

  • Choledochal cysts are congenital biliary dilatations, but soft tissue growth within the common bile duct (CBD) necessitates further investigation.
  • Embryonal rhabdomyosarcoma is a rare malignancy that can occur in various locations, including the biliary tract in children.

Observation:

  • A 10-year-old boy presented with symptoms initially suggestive of a choledochal cyst.
  • Laparotomy revealed necrotic tissue and a soft tissue mass within the CBD.
  • Histopathology and immunohistochemistry confirmed the diagnosis of embryonal rhabdomyosarcoma.

Findings:

  • The patient underwent surgical intervention with T-tube placement for bile duct management.
  • Adjuvant chemotherapy with the VAC regimen (Vincristine, Actinomycin-D, Cyclophosphamide) was administered.
  • Post-treatment imaging demonstrated complete resolution of the tumor mass in the CBD.

Implications:

  • This case highlights the importance of thorough histopathological examination for accurate diagnosis of biliary tract masses in children.
  • Multimodal treatment including surgery and chemotherapy can achieve favorable outcomes for embryonal rhabdomyosarcoma of the CBD.
  • Successful management led to T-tube removal and a positive long-term prognosis for the patient.