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Related Concept Videos

Drug Therapy01:28

Drug Therapy

74
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
74
Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

277
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
277
Antidepressant Drugs: Overview01:25

Antidepressant Drugs: Overview

597
Antidepressant drugs are a class of medications primarily used for treating various mood disorders, including major depression, anxiety disorders, and other related conditions. These medicines work by modulating the neurotransmitter balance within the brain, alleviating depressive symptoms. Antidepressants can be broadly categorized into several groups according to their mechanism of action and chemical structure: Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine...
597
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

170
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
170
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

336
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
336
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

552
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
552

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Related Experiment Video

Updated: Jul 24, 2025

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
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Psychiatric Deprescribing: A Narrative Review.

Shari L Harding1, Kerri A Ellis2, John Boisseau3

  • 1Shari L. Harding, DNP, PMHNP-BC, CPRP, University of Massachusetts Chan Medical School, Worcester, MA, USA.

Journal of the American Psychiatric Nurses Association
|July 1, 2023
PubMed
Summary
This summary is machine-generated.

Psychiatric deprescribing, reducing or stopping psychiatric medications, aims to improve health and minimize risks. This review synthesizes literature to guide clinical practice and future research on this complex intervention.

Keywords:
deprescriptionsdrug taperingmental disorderspolypharmacy

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Area of Science:

  • Psychiatry
  • Pharmacology
  • Clinical Practice

Background:

  • Psychiatric deprescribing involves reducing or discontinuing psychiatric medications.
  • The primary goal is to enhance patient health and mitigate medication-related risks.

Purpose of the Study:

  • To synthesize existing literature on psychiatric deprescribing.
  • To discuss implications for clinical practice and future research.

Main Methods:

  • A systematic literature search was conducted between May and September 2022.
  • Twenty-nine relevant articles were identified, reviewed, and synthesized.

Main Results:

  • Psychiatric deprescribing is a multifaceted process influenced by various facilitators and barriers.
  • The current literature highlights knowledge gaps and offers insights for practice and research.

Conclusions:

  • Despite being a clinical priority, psychiatric deprescribing faces significant implementation barriers.
  • Further research is needed to establish evidence-based practices and support deprescribing initiatives.