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Alginate-based materials for enzyme encapsulation.

Yilun Weng1, Guangze Yang2, Yang Li1

  • 1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD 4072, Australia.

Advances in Colloid and Interface Science
|July 1, 2023
PubMed
Summary
This summary is machine-generated.

Enzyme encapsulation using alginate materials enhances enzyme stability and activity in industrial settings. This review explores alginate-based systems for stabilizing enzymes against harsh conditions, improving their industrial applications.

Keywords:
AlginateEnzyme encapsulationFabrication techniquesIndustrial applicationsRelease

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Area of Science:

  • Biotechnology
  • Materials Science
  • Chemical Engineering

Background:

  • Enzymes offer high efficiency and selectivity but suffer from low stability in industrial processes.
  • Environmental stresses like extreme temperature, pH, and proteases reduce enzyme catalytic activity.
  • Encapsulation stabilizes enzymes by protecting them from these detrimental factors.

Purpose of the Study:

  • To review alginate-based encapsulation systems for enzyme stabilization.
  • To explore industrial applications of stabilized enzymes.
  • To discuss preparation, release mechanisms, and characterization of alginate-enzyme composites.

Main Methods:

  • Ionic gelation of alginate to form enzyme-loaded gel beads.
  • Review of various alginate-based encapsulation strategies.
  • Analysis of enzyme release kinetics and stability.

Main Results:

  • Alginate materials effectively stabilize enzymes through encapsulation.
  • Alginate encapsulation protects enzymes from extreme temperatures, pH, solvents, and proteases.
  • Alginate-based systems demonstrate significant potential for diverse industrial applications.

Conclusions:

  • Alginate encapsulation is a viable strategy for enhancing enzyme stability and performance.
  • Alginate-enzyme composites offer improved enzyme longevity and reusability in industrial processes.
  • Further research into alginate encapsulation can unlock broader industrial enzyme applications.