Related Experiment Video
Updated: Jul 24, 2025

09:00
The Rabbit Blood-shunt Model for the Study of Acute and Late Sequelae of Subarachnoid Hemorrhage: Technical Aspects
Published on: October 2, 2014
13.7K
Measuring coagulopathy in pediatric craniofacial surgery
Alexandra J Borst1, Christopher M Bonfield2, Poornachanda S Deenadayalan3
1Division of Hematology, Children's Hospital of Philadelphia, Pennsylvania.
Summary
Hematologic and coagulation tests can predict blood loss in pediatric complex cranial vault reconstruction (CCVR). However, these standard lab values offer limited insight into the specific mechanisms of coagulopathy during craniofacial surgery.
Area of Science:
- Pediatric Surgery
- Hematology
- Coagulation Science
Background:
- Complex cranial vault reconstruction (CCVR) for craniosynostosis is a major surgical procedure.
- Understanding factors predicting blood loss is crucial for patient management.
Conclusions:
- Standard hematologic and coagulation tests can predict blood loss in pediatric CCVR.
- These laboratory parameters provide limited mechanistic insight into coagulopathy in this surgical context.
- Further research may be needed to elucidate specific coagulopathic mechanisms in craniofacial surgery.

