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Leveraging the Adolescent Brain Cognitive Development Study to improve behavioral prediction from neuroimaging in
Carolina Makowski1,2, Timothy T Brown3, Weiqi Zhao1,4
1Center for Multimodal Imaging and Genetics, University of California San Diego, La Jolla, California, USA.
Biorxiv : the Preprint Server for Biology
|July 3, 2023
Summary
Large-scale brain imaging studies can identify reproducible brain-behavior links. Multivariate methods applied to magnetic resonance imaging (MRI) data require small replication samples for cognitive trait prediction.
Area of Science:
- Neuroimaging
- Developmental Neuroscience
- Cognitive Neuroscience
Background:
- Magnetic resonance imaging (MRI) is widely used to link brain structure and function to human traits.
- Recent studies question the predictive power of MRI for cognitive traits, citing low behavioral variability.
- The Adolescent Brain Cognitive Development (ABCD) Study provides large-scale data for investigating reproducibility.
Conclusions:
- Neuroimaging plays a crucial role in translational neurodevelopmental research.
- Large-scale findings can guide reproducible brain-behavior association studies in smaller samples.
- Multivariate approaches enhance the power and efficiency of neuroimaging research.
