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Coronary Artery Disease in Patients with Severe Mental Illness

Brian Tam To1, Roman Roy1, Narbeh Melikian1,2

  • 1Cardiovascular Department, King's College Hospital NHS Foundation Trust London, UK.

Interventional Cardiology (London, England)
|July 3, 2023
PubMed

Insights

Patients with severe mental illnesses (SMI) face significantly reduced life expectancy due to cardiovascular disease. This review examines coronary artery disease management in SMI patients, highlighting critical research needs.

Area of Science:

  • Cardiology
  • Psychiatry
  • Public Health

Background:

  • Severe mental illnesses (SMI), including schizophrenia and bipolar disorder, drastically reduce life expectancy by up to 20 years.
  • Cardiovascular disease (CVD) is the primary cause of premature death in individuals with SMI.
  • SMI is linked to heightened cardiovascular risk factors and earlier onset of CVD.

Purpose of the Study:

  • To review the current management strategies for coronary artery disease (CAD) in patients with SMI.
  • To identify gaps in treatment and highlight areas for future research in this population.

Main Methods:

  • This study is a narrative review of existing literature.
  • The review synthesizes information on the intersection of SMI, cardiovascular risk, and CAD management.

Main Results:

  • Patients with SMI experience worse prognoses after acute coronary syndrome (ACS).
  • These patients are less likely to receive recommended invasive treatments for CAD.
  • There is a clear need for improved cardiovascular care pathways for individuals with SMI.

Conclusions:

  • Effective management of CAD in SMI patients requires tailored approaches.
  • Further research is crucial to address disparities in cardiovascular care and improve outcomes for individuals with SMI.

Keywords:
Coronary artery diseaseacute coronary syndromebipolar disorderschizophreniasevere mental illness

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