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Updated: May 31, 2026
05:31
Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
Cardiac Valve Repair and Replacement: Are Transcatheter Options Here to Stay?
Samuel Rustem Panday1,2, Fatemeh Habibi Nameghi2, Federico Giacobbe3
1Department of Cardiology, King's College Hospital, SE5 9RS London, UK.
Summary
Transcatheter valve therapies offer safe and effective treatments for valvular heart disease (VHD) across a wider patient range. These minimally invasive options complement traditional surgery, improving patient care and outcomes.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Valvular heart disease (VHD) significantly impacts global health, causing substantial morbidity and mortality.
- Transcatheter therapies have revolutionized VHD management over the last two decades.
- These interventions are increasingly used across diverse patient risk profiles.
Purpose of the Study:
- To review the evolution and current role of transcatheter valve therapies.
- To compare transcatheter approaches with traditional surgical methods.
- To highlight the importance of multidisciplinary decision-making in VHD treatment.
Main Methods:
- Review of landmark trials and guideline endorsements for transcatheter therapies.
- Analysis of the integration of surgical and transcatheter approaches.
- Emphasis on patient selection based on individual factors.
Main Results:
- Transcatheter aortic valve implantation (TAVI), mitral transcatheter edge-to-edge repair (M-TEER), tricuspid transcatheter edge-to-edge repair (T-TEER), and transcatheter valve replacement (TTVR) are established treatments.
- Transcatheter therapies provide safe and effective options for older patients, including those with frailty or comorbidities.
- Surgery remains the gold standard for younger, low-risk patients requiring long-term durability.
Conclusions:
- Transcatheter therapies are expanding access to definitive VHD treatment.
- A multidisciplinary Heart Team approach is crucial for personalized treatment decisions.
- Advancements in technology and expertise will further refine integrated surgical and transcatheter strategies.
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