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Updated: Jul 24, 2025

Author Spotlight: Advancing Biopsy Techniques with Transesophageal Ultrasound
Published on: November 21, 2023
Evolution of interventional endoscopic ultrasound
Mark J Radlinski1, Daniel S Strand1, Vanessa M Shami1
1Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, VA, USA.
Endoscopic ultrasound (EUS) has advanced from diagnosis to intervention, offering diverse applications in gastrointestinal, pancreaticobiliary, and liver procedures. This review details the evolution and future of EUS-guided interventions.
Area of Science:
- Gastroenterology
- Medical Imaging
- Interventional Endoscopy
Background:
- Endoscopic ultrasound (EUS) emerged in the 1980s as a diagnostic tool.
- Advancements in linear echoendoscopes have transformed EUS into an interventional modality.
- EUS now plays a crucial role in assessing the gastrointestinal tract and adjacent organs.
Purpose of the Study:
- To review the origins and evolution of EUS-guided interventional techniques.
- To categorize current EUS applications in luminal, pancreaticobiliary, and hepatic interventions.
- To explore future directions in EUS-guided therapy.
Main Methods:
- Review of the historical development of EUS applications.
- Categorization of interventional EUS procedures.
- Discussion of current techniques and future prospects.
Main Results:
- EUS applications are broadly categorized into transluminal drainage/access, injection therapy, and liver interventions.
- Specific procedures include pancreatic fluid collection management, biliary/pancreatic duct drainage, and enteral anastomosis.
- Liver applications encompass biopsy, portal pressure gradient measurement, and vascular therapies.
Conclusions:
- EUS has evolved into a versatile interventional platform.
- Current EUS techniques address a wide range of gastrointestinal and hepatobiliary conditions.
- Future directions promise further innovation in EUS-guided therapeutic interventions.
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