Related Experiment Video

Updated: Jul 24, 2025

Preparation and Implantation of Electrodes for Electrically Kindling VGAT-Cre Mice to Generate a Model for Temporal Lobe Epilepsy
09:29

Preparation and Implantation of Electrodes for Electrically Kindling VGAT-Cre Mice to Generate a Model for Temporal Lobe Epilepsy

Published on: August 17, 2021

2.4K

Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse

Bi-Rong Cao1,2, Yi-Ming Huang3, Fu-Yun Tian1,4

  • 1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.

Acta Pharmacologica Sinica
|July 4, 2023
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

Use of Freeze-thawed Embryos for High-efficiency Production of Genetically Modified Mice
06:46

Use of Freeze-thawed Embryos for High-efficiency Production of Genetically Modified Mice

Published on: April 2, 2020

9.8K
A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
06:58

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy

Published on: July 12, 2021

5.0K

Related Experiment Videos

Last Updated: Jul 24, 2025

Preparation and Implantation of Electrodes for Electrically Kindling VGAT-Cre Mice to Generate a Model for Temporal Lobe Epilepsy
09:29

Preparation and Implantation of Electrodes for Electrically Kindling VGAT-Cre Mice to Generate a Model for Temporal Lobe Epilepsy

Published on: August 17, 2021

2.4K
Use of Freeze-thawed Embryos for High-efficiency Production of Genetically Modified Mice
06:46

Use of Freeze-thawed Embryos for High-efficiency Production of Genetically Modified Mice

Published on: April 2, 2020

9.8K
A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
06:58

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy

Published on: July 12, 2021

5.0K

Related Concept Videos

In-vitro Mutagenesis01:16

In-vitro Mutagenesis

14.0K
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
14.0K

Articles linked to this work by shared authors, journal, and citation graph.

Lvguidingan inhibits Nav1.2 and epilepsy-associated SCN2A gain-of-function variants.

Acta pharmacologica Sinica·2026

Biosynthesis of Crinipellin Diterpenes in Mushroom Marasmius fiardii PR-910.

Journal of the American Chemical Society·2026

Divergent Biosynthetic Routes Encoded by a Single Gene Cluster in Shikimate-Derived Fungal Meroterpenoid Biosynthesis.

Organic letters·2026

Ibuprofen for hemodynamically significant patent ductus arteriosus in extremely preterm infants: a target trial emulation.

Translational pediatrics·2026

Bifunctional Structural Regulation of Polymer Composites for High-Efficiency Electromagnetic Wave Absorption and Heat Dissipation.

Small (Weinheim an der Bergstrasse, Germany)·2026

Drimane Sesquiterpenes Isolated from the Fruiting Body of the Clavarioid Fungus Ramaria botrytoides.

Molecules (Basel, Switzerland)·2026

Small-molecule-induced neuron-specific hypoxia: recapitulating developmental angiogenesis for ischemic stroke therapy.

Acta pharmacologica Sinica·2026

Neutrophil extracellular traps in liver diseases: from molecular mechanisms to therapeutic interventions.

Acta pharmacologica Sinica·2026

Deeper delving Nav1.8 inhibitor Suzetrigine in chronic pain.

Acta pharmacologica Sinica·2026

The RNA structural code: orchestrating gene expression and enabling precision therapies.

Acta pharmacologica Sinica·2026

Structural basis for small-molecule agonism at GCGR and GIPR via a conserved intracellular allosteric site.

Acta pharmacologica Sinica·2026

Fast Electronic Memristors with Improved Retention and Synaptic Functionality Enabled by Tri-TaOx Engineering.

ACS applied materials & interfaces·2026

Feasibility of Electrode-Location Estimates Based on Preoperative CT-Imaging for Anatomy-Based Fitting in Cochlear Implant Recipients.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·2026

Revalidating KCrPDTA for aqueous redox flow batteries.

EES batteries·2026

Combined Application of a Helix-Fixation Leadless Pacemaker and a Subcutaneous Implantable Cardioverter-Defibrillator in a Dialysis Patient: A Case Report.

Clinical case reports·2026

PointSenseNet: A Hierarchical Point-Cloud-Based Reconstruction Framework with Application to Localized Inverse Electrocardiographic Mapping.

IEEE transactions on bio-medical engineering·2026

Adaptive Network Stabilization Despite Profound Structural Reorganization in Human Organotypic Cultures.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us