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[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
A TBADT photocatalyst-enabled radical-induced cyclization pathway to access functionalized dihydrobenzofurans
Punith S Gowda1, Duddu S Sharada2, Gedu Satyanarayana1
1Department of Chemistry, Indian Institute of Technology (IIT) Hyderabad, Kandi, Sangareddy, Telangana 502284, India. gvsatya@chy.iith.ac.in.
Abstract:
Herein, this work describes a photoinduced visible light-mediated radical cyclization for constructing dihydrobenzofuran (DHB) scaffolds. Notably, this cascade photochemical process is tolerable with various aromatic aldehydes and diverse alkynyl aryl ethers and proceeds via an intramolecular 1,5-hydrogen atom transfer (HAT) pathway. Significantly, acyl C-H activation under mild conditions has been achieved without the use of additives or reagents. The photocatalyst, tetrabutylammonium decatungstate (TBADT), plays an important role in the present strategy by facilitating the well-known hydrogen atom transfer during the course of the reaction.
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