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Related Concept Videos

Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

410
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
410
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

150
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
150
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

116
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
116
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

115
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
115
Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

424
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
424
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

380
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
380

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Related Experiment Video

Updated: Jul 24, 2025

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
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Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice

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Acute Pancreatitis Review.

Yuting Huang1, Dilhana S Badurdeen1

  • 1Department of Gastroenterology and Hepatology, Mayo Clinic, FL, USA.

The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology
|July 5, 2023
PubMed
Summary
This summary is machine-generated.

Acute pancreatitis management has evolved, emphasizing moderate fluid resuscitation and early enteral feeding. Current guidelines and new research guide improved patient care, reducing complications and mortality.

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Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
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Area of Science:

  • Gastroenterology
  • Clinical Medicine
  • Internal Medicine

Background:

  • Acute pancreatitis incidence is increasing by approximately 3% annually.
  • Existing guidelines from 2013 and 2018 require updates due to recent milestone studies.
  • The condition poses a significant threat with potentially devastating consequences.

Purpose of the Study:

  • To review current acute pancreatitis guidelines.
  • To provide an update on clinical practice-changing literature.
  • To inform evidence-based clinical decision-making for acute pancreatitis management.

Main Methods:

  • Systematic review of current acute pancreatitis guidelines.
  • Analysis of recent milestone studies and clinical practice-changing literature.
  • Inclusion of findings from trials like WATERFALL and anticipated GOULASH trial insights.

Main Results:

  • Moderate aggressive fluid resuscitation with lactated Ringer's solution is recommended (WATERFALL trial).
  • Prophylactic antibiotics are not recommended; early enteral feeding reduces morbidity.
  • Individualized pain management and consideration of epidural analgesia for severe cases are advised.

Conclusions:

  • Acute pancreatitis management has significantly evolved with new research.
  • Early enteral nutrition and appropriate fluid resuscitation are key to reducing morbidity.
  • Ongoing research in electrolytes, pharmacologic agents, anticoagulants, and nutrition support will further refine patient care.