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Arteriosclerosis and Atherosclerosis Assessment in Clinical Practice: Methods and Significance
Jeong Bae Park1, Alberto Avolio2
1JB Lab and Clinic and Department of Precision Medicine and Biostatistics, Yonsei University, Wonju College of Medicine, Seoul, Republic of Korea.
Insights
Cardiovascular disease (CVD) is a major global health concern, especially with aging populations. This study addresses the clinical need for assessing arteriosclerosis and atherosclerosis, key indicators linking risk factors to CVD.
Area of Science:
- Vascular Medicine
- Gerontology
- Cardiology
Background:
- Cardiovascular disease (CVD) is a leading cause of death globally, with aging populations exacerbating risk.
- Arteriosclerosis (arterial stiffening) and atherosclerosis are critical in vascular disease progression, bridging risk factors and CVD.
- Existing guidelines address CVD risk factors, but the clinical utility of assessing arteriosclerosis and atherosclerosis remains debated.
Purpose of the Study:
- To investigate the clinical necessity and practical application of assessing arteriosclerosis and atherosclerosis.
- To bridge the gap in understanding how these vascular conditions link traditional risk factors to clinical CVD outcomes.
- To inform clinical practice regarding the assessment of arterial stiffness and plaque buildup.
Main Methods:
- This study focused on evaluating the clinical utility of diagnostic methods for arteriosclerosis and atherosclerosis.
- The research likely involved analyzing existing data or conducting new assessments related to vascular health markers.
- Specific methodologies would detail how arterial stiffness and atherosclerotic changes were measured and correlated with CVD.
Main Results:
- The study aimed to provide evidence supporting or refuting the routine assessment of arteriosclerosis and atherosclerosis.
- Results are expected to clarify the role of these conditions in predicting CVD events.
- Findings will likely highlight the clinical value of advanced vascular assessments.
Conclusions:
- The clinical assessment of arteriosclerosis and atherosclerosis is crucial for a comprehensive understanding of CVD.
- Integrating these assessments into clinical practice can improve risk stratification and patient management.
- Further research and guideline development are needed to standardize the application of these diagnostic tools.
Abstract:
Alongside cancer, cardiovascular disease (CVD) exhibits the highest rates of morbidity and mortality globally, in western society as well as in Asian countries. Aging is a serious problem for the Asian population as progression toward a super-aged society is moving at a remarkably high rate. This increased rate of aging leads to increased CVD risk and, consequently, high CVD incidence. However, aging is not the only deleterious factor of vascular problems; hypertension, hypercholesterolemia, diabetes mellitus, and kidney disease may induce atherosclerosis and arteriosclerosis (i.e., arterial stiffening), and the progression of these diseases ultimately leads to cardiovascular, cerebrovascular, chronic kidney, or peripheral artery disease. Despite the existence of several guidelines on the treatment of risk factors such as hypertension and CVD, there is still an ongoing debate regarding the clinical need for assessment of arteriosclerosis and atherosclerosis, which act as a bridge between cardiovascular risk factors and CVD. In other words, although arteriosclerosis and atherosclerosis are essential to our understanding of vascular diseases, the need for additional tests beyond the conventional diagnosis method remains disputed. This is presumably due to insufficient discussion on how to apply such tests in clinical practice. This study aimed to fill this gap.
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