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Updated: Jul 24, 2025

Stereotactically-guided Ablation of the Rat Auditory Cortex, and Localization of the Lesion in the Brain
Published on: October 11, 2017
Deafness induces complete crossmodal plasticity in a belt region of dorsal auditory cortex
Yaser Merrikhi1, Ali Mirzaei2, Melanie A Kok3
1Department of Physiology, Faculty of Medicine, McGill University, Montreal, Quebec, Canada.
Abstract:
Many neural areas, where patterned activity is lost following deafness, have the capacity to become activated by the remaining sensory systems. This crossmodal plasticity can be measured at perceptual/behavioural as well as physiological levels. The dorsal zone (DZ) of auditory cortex of deaf cats is involved in supranormal visual motion detection, but its physiological level of crossmodal reorganisation is not well understood. The present study of early-deaf DZ (and hearing controls) used multiple single-channel recording methods to examine neuronal responses to visual, auditory, somatosensory and combined stimulation. In early-deaf DZ, no auditory activation was observed, but 100% of the neurons were responsive to visual cues of which 21% were also influenced by somatosensory stimulation. Visual and somatosensory responses were not anatomically organised as they are in hearing cats, and fewer multisensory neurons were present in the deaf condition. These crossmodal physiological results closely correspond with and support the perceptual/behavioural enhancements that occur following hearing loss.
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