[Histological changes in the liver of the rat with experimental small intestinal shunt]

Histological alterations in liver of rats 6 and 12 weeks after bypass of lower third of small intestine are described. Six weeks after the operation signs of reactive inflammation in liver appeared. By the 12th week after the operation these alterations decreased. Restriction of nutrition in time and quantity leads to enhancement of the alterations, with the tendency to liver fibrosis. The results confirm the opinion about malnutrition as important factor in etiology of liver damage after bypass of small intestine.