[Paraproteins in dermatological patients (author's transl)]

Report on paraprotein-cases in a dermatological totality of patients during a six years period. Among 860 seras we found 22 cases with paraproteins. Except IgE-paraprotein all other paraproteinclasses were found in their natural multidy. In 2 cases we saw Bence-Jones-protein, in an other case a very rare combination of IgD-paraprotein with Amyloidosis cutis nodularis atrophicans Gottron. Diseases with sure or probable autoimmune background, i.e. diseases of the vessels with a possible dependence from cold and malignant tumours were on the top of paraproteinemia. 4 of 22 patients died during a 3 years' period after detection of paraprotein. Common clinical and paraclinical signs and symptoms of paraproteinoses are collected in a special table.