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Author Spotlight: Decoding Corneal Neovascularization with Alkali Burn Model for Future Therapeutic Strategies
Published on: June 30, 2023
Demographic profile and clinical characteristics of patients presenting with acute ocular burns
Anahita Kate1, Supriya Sharma2, S Yathish3
1Shantilal Shanghvi Cornea Institute, L V Prasad Eye Institute, Vijayawada, Andhra Pradesh, India.
Insights
Acute ocular burns (AOB) disproportionately affect children, with domestic injuries and specific agents like edible lime being common. Children experienced more severe burns and poorer visual outcomes, highlighting the need for targeted prevention strategies.
Area of Science:
- Ophthalmology
- Trauma Care
- Public Health
Background:
- Acute ocular burns (AOB) represent a significant cause of ocular morbidity.
- Understanding the demographic and clinical differences between pediatric and adult AOB is crucial for effective management and prevention.
Purpose of the Study:
- To compare the demographic and clinical characteristics of acute ocular burns in children and adults.
- To identify specific risk factors and causative agents in pediatric versus adult AOB.
- To analyze treatment outcomes and visual acuity in different age groups.
Main Methods:
- A retrospective case series analysis of 271 children and 1300 adults with AOB treated at two tertiary eye care centers.
- Data collection included demographics, causative agents, injury severity (Dua grade), presenting and final visual acuity (VA), and treatments received.
- Statistical analysis was performed to compare outcomes between pediatric and adult cohorts.
Main Results:
- Males were more frequently affected, especially in the adult group. Domestic injuries predominated in children (79%), while workplace injuries were more common in adults (59%).
- Alkali and acids were the primary causes, with edible lime (chuna), superglue, and firecrackers being significant agents in children. Adults commonly encountered chuna, insecticides, lye, and superglue.
- Children had a higher incidence of severe burns (Dua grade IV-VI) and required more interventions like amniotic membrane grafting and tarsorrhaphy. Presenting visual acuity was poorer in children, and final visual acuity for severe burns was also worse compared to adults.
Conclusions:
- The study highlights distinct patterns in AOB etiology and severity between children and adults.
- Specific agents and injury settings necessitate targeted public health awareness and preventive measures for children.
- Addressing these age-specific factors is essential to reduce avoidable ocular morbidity from acute ocular burns.
Purpose:
To study and compare the demographic and clinical profile of acute ocular burns (AOB) in children and adults.
Methods:
This retrospective case series included 271 children (338 eyes) and 1300 adults (1809 eyes) who presented to two tertiary eye care centers within one month of sustaining AOB. Data regarding demographics, causative agents, severity of injury, visual acuity (VA), and treatment were collected and analyzed.
Results:
Males were more commonly affected particularly among adults (81% versus 64%, P < 0.00001). Among children, 79% sustained domestic injuries, whereas 59% of adults had work-place injuries (P < 0.0001). Most cases were due to alkali (38%) and acids (22%). Edible lime (chuna, 32%), superglue (14%), and firecrackers (12%) in children, and chuna (7%), insecticides, lye, superglue (6% each), toilet cleaner (4%) and battery acid (3%) in adults, were the main causative agents. The percentage of cases with Dua grade IV-VI was greater in children (16% versus 9%; P = 0.0001). Amniotic membrane grafting and/or tarsorrhaphy were needed in 36% and 14% of affected eyes in children and adults, respectively (P < 0.00001). The median presenting VA was logMAR 0.5 in children and logMAR 0.3 in adults (P = 0.0001), which improved significantly with treatment in both groups (P < 0.0001), but the final VA in eyes with Dua grade IV-VI burns was poorer in children (logMAR 1.3 versus logMAR 0.8, P = 0.04).
Conclusion:
The findings clearly delineate the at-risk groups, causative agents, clinical severity, and treatment outcomes of AOB. Increased awareness and data-driven targeted preventive strategies are needed to reduce the avoidable ocular morbidity in AOB.
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