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CRISPR-engineered deletion of POGZ alters transcription factor binding at promoters of genes involved in synaptic signaling.

Clinical, in vitro, and in vivo evidence of WAPL as a cohesinopathy-associated gene and phenotypic driver of 10q22.3q23.2 genomic disorder.

Integration of genetic evidence to identify approved drug targets.

Genome-wide association study of untargeted plasma metabolomic profiles identifies host genetic regulation in people with HIV.

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