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Clinical Outcomes in Hypertensive Emergency: A Systematic Review and Meta-Analysis
Tariq Jamal Siddiqi1, Muhammad Shariq Usman1, Ahmed Mustafa Rashid2
1Department of Medicine University of Mississippi Medical Center Jackson MS USA.
Hypertensive emergencies in the emergency department often involve brain and heart damage, with ischemic stroke being most common. These emergencies carry significant risks of mortality and hospitalization.
Area of Science:
- Cardiology
- Neurology
- Emergency Medicine
Background:
- Hypertensive emergencies are critical medical conditions requiring prompt attention.
- Understanding the patterns of organ damage and patient outcomes is crucial for effective management.
Approach:
- A systematic review and meta-analysis of 15 studies involving 4370 patients presenting to emergency departments.
- PubMed database was queried for studies published up to November 30, 2021.
Key Points:
- Hypertensive emergencies occurred in 0.5% of all ED visits and 35.9% of patients with hypertensive crisis.
- The most common hypertension-mediated organ damage included ischemic stroke (28.1%), pulmonary edema/acute heart failure (24.1%), and hemorrhagic stroke (14.6%).
- In-hospital mortality for hypertensive emergencies was 9.9%.
Conclusions:
- Hypertension-mediated organ damage in the ED primarily affects the brain and heart.
- Patients with hypertensive emergencies face significant cardiovascular and renal morbidity and mortality.
- These findings highlight the need for vigilant monitoring and management of hypertensive emergencies in the ED setting.
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