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Blood Pressure Outcomes Among US Veterans Initiating Hypertension Treatment, 2014 to 2023
Catherine G Derington1,2, Haojia Li3, Yue Zhang3
1Department of Medicine, University of Colorado School of Medicine, Aurora (C.G.D., S.R.).
Insights
Despite guideline changes and the COVID-19 pandemic, hypertension management in Veterans showed minimal improvement. Blood pressure (BP) control rates remained low, highlighting persistent clinical inertia in early hypertension treatment.
Area of Science:
- Cardiovascular Medicine
- Public Health
- Health Services Research
Background:
- Persistently low blood pressure (BP) control rates and therapeutic inertia pose significant challenges in hypertension management.
- Evaluating trends in BP before and after major healthcare disruptions is crucial for understanding early hypertension management.
Purpose of the Study:
- To assess the impact of a 2017 target-lowering guideline and the COVID-19 pandemic on early hypertension management.
- To analyze trends in pre- and posttreatment BP control in Veterans newly diagnosed with hypertension.
Main Methods:
- Retrospective cohort study using national Veterans Health Administration data (2014-2023).
- Included outpatients newly diagnosed with hypertension and starting medication.
- Stratified patients into pre-guideline/prepandemic, post-guideline/prepandemic, and post-guideline/postpandemic periods.
- Analyzed mean posttreatment systolic BP (SBP) and BP control rates (<140/90 and <130/80 mm Hg) at 1 year.
Main Results:
- Adjusted posttreatment SBP showed minimal variation across periods for different baseline SBP groups.
- BP control rates (<140/90 mm Hg) at 1 year ranged from 46.4% to 84.2%, with slight increases across periods.
- BP control rates (<130/80 mm Hg) at 1 year were low, ranging from 15.1% to 40.0%, with minimal changes across periods.
Conclusions:
- Despite a target-lowering guideline and the pandemic, BP levels and control in Veterans remained largely unchanged.
- A significant proportion of Veterans did not achieve recommended BP targets within one year of treatment initiation.
- Persistent clinical inertia necessitates improved strategies for early hypertension management within the Veterans Health Administration.
Background:
Amid persistently low blood pressure (BP) control rates and pervasive therapeutic inertia, we evaluated trends in pre- and posttreatment BP before and after 2 major disruptions (the 2017 target‑lowering guideline and the COVID‑19 pandemic) to assess their impact on early hypertension management.
Methods:
This retrospective cohort study of national Veterans Health Administration data included outpatient adults newly diagnosed with hypertension and starting antihypertensive medication between November 13, 2014, and May 31, 2023 (index date). Patients were stratified into 3 periods corresponding to preguideline/prepandemic (Period 1), postguideline/prepandemic (Period 2), and postguideline/postpandemic (Period 3), and into 3 pretreatment systolic BP (SBP) groups based on the average of ≥2 measurements in the 90-day preindex period (<140, 140-160, or ≥160 mm Hg). Across periods, multivariable analyses evaluated: (1) mean posttreatment SBP (mean of measurements from days 180-365 postindex); and (2) posttreatment BP control (<140/90 or <130/80 mm Hg).
Results:
Among 271 496 Veterans (mean age, 62 years; 92% male; 66% non-Hispanic White), 39%, 32%, and 29% were in Periods 1, 2, and 3, respectively. Adjusted posttreatment SBP across periods was 128, 135, and 142 mm Hg for the <140, 140 to 160, and ≥160 groups, respectively. Rates of posttreatment BP control <140/90 mm Hg across Periods 1, 2, and 3, respectively, were 82.3%, 83.3%, and 84.2% (SBP <140 group); 64.1%, 66.1%, and 67.3% (140-160 group); and 46.4%, 47.0%, and 48.6% (≥160 group). For BP control <130/80 mm Hg, rates were 38.2%, 40.0%, and 39.9% (SBP <140 group); 20.7%, 22.0%, and 22.6% (140-160 group); and 15.1%, 15.4%, and 15.2% (≥160 group).
Conclusions:
Despite the target-lowering guideline and the care-disrupting pandemic, BP levels and control among Veterans remained largely unchanged. At 1 year, only half to two-thirds achieved BP <140/90 mm Hg, and few reached <130/80 mm Hg, underscoring persistent clinical inertia and the need to improve early hypertension management in the Veterans Health Administration.
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