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Updated: Jul 24, 2025
Ultrasonographic Evaluation of Breast Cancer-related Lymphedema
Published on: January 12, 2017
Lymphography using microbubbles and contrast-enhanced ultrasound (CEUS) before lymphatic supermicrosurgery for severe
Jia Zhu1, Xiaoting Yu1, Lili Zhang2
1Department of General Surgery, The First Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi, China.
Abstract:
Lymphaticovenous anastomosis (LVA) is an effective surgical treatment for lymphorrhea. However, the traditional indocyanine green (ICG) fluorescent lymphography mapping for lymphatic vessels has limitations, it can only depict the initial capillary lymphatic network localized in the dermis of the skin, which cannot visualize lymphatics deeper than 1.5 cm. A new mapping technique, microbubbles and contrast-enhanced ultrasound (CEUS) can address the problem. In one case of lymphocutaneous fistula, for the first time, we used microbubbles and CEUS technique for preoperative localization for LVAs. Microbubbles and CEUS can identify deep lymphatic vessels and better evaluate the function of lymphatic vessels. The patient's symptoms of edema and lymphorrhea improved clinically. Microbubbles and CEUS is an effective methods for identifying lymphatic vessels in lower limbs.
