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Personalizing precision medicine: Patients with AML perceptions about treatment decisions
Åsa Grauman1, Mika Kontro2, Karl Haller3
1Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
Patient Education and Counseling
|July 8, 2023
Summary
Patients with acute myeloid leukemia desire more information for shared decision-making in precision medicine. Lack of knowledge hinders involvement, emphasizing the physician
Area of Science:
- Oncology
- Genetics
- Medical Ethics
Background:
- Acute myeloid leukemia (AML) presents complex treatment decisions.
- Precision medicine offers personalized therapeutic strategies for AML.
- Patient involvement in shared decision-making is evolving.
Purpose of the Study:
- To explore AML patients' perceptions of precision medicine.
- To understand patient preferences for involvement in precision medicine decision-making.
- To identify barriers and facilitators for patient engagement.
Main Methods:
- Semi-structured interviews conducted across three European countries (Finland, Italy, Germany).
- Study included 16 patients aged 24-79 years.
- Thematic content analysis used to analyze interview data.
Main Results:
- Patients perceive a lack of knowledge as a significant barrier to decision-making.
- Treatment choices are often based on physician trust and intuition, especially in urgent situations.
- Patients express willingness to accept treatments with low cure probabilities due to their critical condition.
Conclusions:
- Patients' understanding of precision medicine and involvement in decision-making pose significant challenges.
- While technical advancements are welcomed, the physician's role as a trusted expert remains paramount.
- Effective patient education is crucial for enhancing perceived involvement in precision medicine.
Keywords:
Acute myeloid leukemia (AML)Patient perceptionPatient preferencesPrecision medicineQualitative designShared decision-makingMore Related Videos
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