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Updated: Jul 24, 2025

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
Synthesis of pyranobenzopyrans from D-glucal using ionic liquids
Sumiea Eltayeb1, Cecilia H Marzabadi1
1Department of Chemistry & Biochemistry, Seton Hall University, 400 South Orange Ave, South Orange, NJ, 07079, USA.
Abstract:
Imidazolium room temperature ionic liquids (RTILs) were used as solvents in the Lewis acid-catalyzed cycloaddition reactions of D-glucal with substituted salicylaldehydes. These reactions selectively led to various, novel, cis-pyrano [4,3-b]benzopyrans in modest yields, different products than those isolated from analogous solution studies. Furan diol was isolated as the major byproduct from all the reactions. The use of RTILs facilitated the use of unprotected sugars in these reactions.
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