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Published on: October 12, 2017
Lower Urinary Tract Obstruction in Newborns
Jaime Flores-Torres1, Amarilis Sanchez-Valle2, Jose R Duncan3
1Division of Neonatology, Department of Pediatrics, Morsani College of Medicine, University of South Florida, Tampa General Hospital, 5 Tampa General Circle HMT 4th Floor, Suite 450, Tampa, FL 33606, USA.
Abstract:
Lower urinary tract obstruction (LUTO) is a rare birth defect with a prevalence between 1 in 5,000 and 1 in 25,000 pregnancies. LUTO is one of the most common causes of congenital abnormalities of the renal tract. Several genetic conditions have been associated with LUTO. Most common causes of LUTO are posterior urethral valves and urethral atresia. Despite available prenatal and postnatal treatments, LUTO is a significant cause of morbidity and mortality in newborns causing significant end stage renal disease and pulmonary hypoplasia.
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