A novel longitudinal rank-sum test for multiple primary endpoints in clinical trials: Applications to

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The Mantel-Cox Log-Rank Test

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Wilcoxon Rank-Sum Test

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Wilcoxon Signed-Ranks Test for Median of Single Population

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Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
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