Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jul 24, 2025

Transpupillary Two-Photon In Vivo Imaging of the Mouse Retina

Transpupillary Two-Photon In Vivo Imaging of the Mouse Retina

Published on: February 13, 2021

SYNAPTOTAGMIN-9 IN MOUSE RETINA.

Chris S Mesnard^1,2, Cassandra L Hays^1,3, Lou E Townsend^1,2

¹Truhlsen Eye Institute and Department of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, NE 68106, USA.

Biorxiv : the Preprint Server for Biology

|July 10, 2023

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hepatocyte-Specific Deletion of Betaine-Homocysteine Methyltransferase Disrupts Methionine Metabolism and Promotes the Spontaneous Development of Hepatic Steatosis.

Biomolecules·2026

Same author

Effects of Growth and Development on Aqueous Humor Dynamics in Male Dutch Belted Rabbits.

Investigative ophthalmology & visual science·2025

Same author

The <i>TECTB-C225Y</i> Variant Causing Autosomal Dominant Deafness in a Nicaraguan Family Enhances Sensitivity to Noise-Induced Hearing Loss in Mice.

medRxiv : the preprint server for health sciences·2025

Same author

The architecture of invaginating rod synapses slows glutamate diffusion and shapes synaptic responses.

The Journal of general physiology·2025

Same author

Geometric tortuosity at invaginating rod synapses slows glutamate diffusion and shapes synaptic responses: insights from anatomically realistic Monte Carlo simulations.

bioRxiv : the preprint server for biology·2024

Same author

Rod inputs arrive at horizontal cell somas in mouse retina solely via rod-cone coupling.

bioRxiv : the preprint server for biology·2024

Same journal

Whole-Embryo 3D Quantification Reveals Conserved Topological Design and Scaling of Germ Layers in Xenopus.

bioRxiv : the preprint server for biology·2026

Same journal

scRNA-seq and genomics analyses reveal key mechanisms of inverted papilloma-associated sinonasal squamous cell carcinoma malignant transformation.

bioRxiv : the preprint server for biology·2026

Same journal

M1C IS NECESSARY FOR DARAXONRASIB RESISTANCE OF NSCLC KRAS(G12C) MUTANT CELLS.

bioRxiv : the preprint server for biology·2026

Same journal

A human-specific genetic modifier reconfigures large-scale cortical network dynamics underlying behavioral performance.

bioRxiv : the preprint server for biology·2026

Same journal

<i>Staphylococcus aureus</i> uses a eukaryotic-like uridyltransferase to make UDP-GlcNAc for cell wall synthesis.

bioRxiv : the preprint server for biology·2026

Same journal

Dynamic redistribution of eIF4F controls cap-dependent translation initiation.

bioRxiv : the preprint server for biology·2026

See all related articles

Synaptotagmin-9 (Syt9) is present in the retina and plays a role in visual processing. Eliminating Syt9 from rods impacts retinal signaling, particularly in bright light conditions.

Area of Science:

Neuroscience
Ophthalmology
Molecular Biology

Background:

Synaptotagmin-9 (Syt9) is a known calcium sensor for fast synaptic release in the brain.
The expression and function of Syt9 in the retina remain largely uncharacterized.

Conclusions:

Syt9 is expressed in the retina and influences visual processing.
Syt9 in rods is critical for regulating visual signaling, particularly under bright light conditions where cone signals are integrated.
Syt9 may modulate the transmission of cone signals by rod pathways.

Keywords:

Synaptotagmin electroretinogram retina rod photoreceptor cell

More Related Videos

Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina

Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina

Published on: May 6, 2015

Immunohistochemical and Calcium Imaging Methods in Wholemount Rat Retina

Immunohistochemical and Calcium Imaging Methods in Wholemount Rat Retina

Published on: October 13, 2014

Related Experiment Videos

Last Updated: Jul 24, 2025

Transpupillary Two-Photon In Vivo Imaging of the Mouse Retina

Transpupillary Two-Photon In Vivo Imaging of the Mouse Retina

Published on: February 13, 2021

Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina

Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina

Published on: May 6, 2015

Immunohistochemical and Calcium Imaging Methods in Wholemount Rat Retina

Immunohistochemical and Calcium Imaging Methods in Wholemount Rat Retina

Published on: October 13, 2014