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Dirofilariasis mouse models for heartworm preclinical research.

A E Marriott1, J L Dagley1, S Hegde1

  • 1Department of Tropical Disease Biology, Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom.

Frontiers in Microbiology
|July 10, 2023
PubMed
Summary

New immunodeficient mouse models offer a promising alternative for heartworm (Dirofilaria immitis) drug screening. These models enable faster, more cost-effective research, potentially reducing the need for cat and dog studies.

Keywords:
Wolbachiadirofilariasisdrug developmentheartwormone healthparasitologypharmacologysymbiosis

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