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Honokiol in glioblastoma recurrence: a case report
Ce Wang1, Zehao Cai1, Yue Huang2
1Department of Neuro-Oncology, Cancer Center, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Frontiers in Neurology
|July 10, 2023
Abstract:
Glioblastoma is the most common and aggressive primary tumor in the central nervous system. There is no standard of care for patients with recurrent GBM. Honokiol is a pleiotropic lignan and has the potential to be a potent and safe anticancer agent in human GBM when it is encapsulated by liposomes. We report an efficient and safe response to three phases of treatment with liposomal honokiol in a patient with recurrent glioblastoma.
Keywords:
blood–brain barrier permeabilityclinical trialglioblastomaliposomal honokioltumor progression
