Single-shot 3D photoacoustic computed tomography with a densely packed array for transcranial functional imaging
Rui Cao1, Yilin Luo1,2, Jinhua Xu1,2
1Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Department of Medical Engineering, California Institute of Technology, Pasadena, CA, USA.
Arxiv
|July 10, 2023
Summary
This study introduces an advanced photoacoustic computed tomography (PACT) system for real-time, label-free functional brain imaging. The novel PACT system overcomes skull limitations for improved transcranial imaging in humans.
Area of Science:
- Biomedical Engineering
- Medical Imaging
- Neuroscience
Background:
- Photoacoustic computed tomography (PACT) offers label-free hemodynamic imaging for functional brain studies.
- Transcranial PACT is limited by acoustic distortions and poor light penetration through the skull.
Conclusions:
- The engineered PACT system effectively overcomes transcranial imaging barriers.
- This technology holds significant potential for real-time, in vivo functional neuroimaging in humans.
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