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Updated: Jul 20, 2026

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Optical Imaging of Neurons in the Crab Stomatogastric Ganglion with Voltage-sensitive Dyes
Published on: March 23, 2011
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AI to the rescue of voltage imaging
Jérôme A Lecoq1, Kaspar Podgorski2, Benjamin F Grewe3,4
1Allen Institute, MindScope program, Seattle, USA.
Cell Reports Methods
|July 10, 2023
Abstract:
In a recent issue of Nature Methods, Platisa et al. present an approach for long-term, in vivo population voltage imaging with single spike resolution across a local population of 100 neurons.1 Key to this step forward was the combination of a customized high-speed two-photon microscope with an optimized, positive-going, genetically encoded voltage indicator and a tailored machine learning denoising algorithm.

