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Association between hypertension and clinical outcomes in COVID-19 patients: a case-controlled study

Fatemeh Aslanbeigi1, Habiballah Rahimi2, Adeleh Malekipour3

  • 1School of Medicine, Kashan University of Medical Sciences.

Annals of Medicine and Surgery (2012)
|July 10, 2023
PubMed

Insights

Hypertension is linked to worse outcomes and increased mortality in coronavirus disease 2019 (COVID-19) patients. Managing blood pressure is crucial for COVID-19 patient care and improving prognosis.

Area of Science:

  • Medicine
  • Public Health
  • Infectious Diseases

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, presents a significant global health challenge.
  • Understanding clinical differences in COVID-19 patients with and without hypertension is vital for effective management.

Purpose of the Study:

  • To compare clinical symptoms and physical findings in hypertensive versus nonhypertensive patients with COVID-19.
  • To assess the impact of hypertension on COVID-19 outcomes and mortality.

Main Methods:

  • A retrospective observational case-control study involving 280 laboratory-confirmed COVID-19 patients.
  • Data on demographics, clinical findings, and comorbidities were extracted from a hospital registry.

Main Results:

  • No significant differences in common symptoms like fever or cough were observed between hypertensive and nonhypertensive groups.
  • COVID-19 mortality was significantly higher in patients with hypertension compared to those without.
  • Older patients exhibited a higher prevalence of underlying diseases.

Conclusions:

  • Hypertension is associated with poorer prognosis and increased mortality in COVID-19 patients.
  • Optimizing blood pressure management is essential for COVID-19 patient care.
  • Early intervention and education for elderly patients with hypertension and comorbidities are important.

Keywords:
clinical manifestationscoronavirushypertensionphysical findings

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