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Updated: Jul 24, 2025

Expression and Purification of Virus-like Particles for Vaccination
Published on: June 2, 2016
English-language videos on YouTube as a source of information Human Papilloma Virus vaccination
Aylin Onder Dirican1, Nazli Topfedaisi Ozkan2, Gizem Bektas2
1Department of Gynecology and Obstetrics, Baskent University Hospital, Ankara, Turkey.
Objective:
To assess the quality of information presented in YouTube videos about human papillomavirus vaccination.
Methods:
The descriptive study was conducted at Konya Meram Education and Research Hospital, On October 15, 2019 when the YouTube website was search using the terms 'human papillomavirus', 'HPV vaccine' and 'Gardasil'. The vide-os were recorded to a playlist by two individual gynaecologists to prevent any change in the listed videos. The videos were categorised into 3 groups; useful in-formation group A, misleading information group B and insufficient information group C. The quality of the videos was scored using global quality scale from 1 = poor quality to 5 = excellent quality. DISCERN scale was used for reliability. A 10-point scale was used to evaluate comprehensiveness of the videos. Data was analysed using SPSS 20.
Results:
Of the 200 videos assessed, 179(89.5%) were analysed. There were 17(9.5%) videos in group A, 38(21.2%) in group B and 124(69.3%) in group C. Mean global quality scale score was 3.94±1.39 group A, 1.84±0.59 group B and 3.13±0.94 group C (p<0.001). Mean reliability values were 4.18±1.13group A, 1.66±0.66 group B and 3.03±0.87 group C (p<0.001). Comprehensiveness scores were 6.94±2.49 group A, 1.53±0.95 group B and 4.87±1.72 group C (p<0.001).
Conclusions:
Professional organisations, university channels and doctors should provide accurate, unbiased and evidence-based information on YouTube for community awareness.
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