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Updated: Jul 23, 2025

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
Published on: January 17, 2020
Diastereoselective guest-shape dependent [2+2]-photodimerization of 2-cyclopenten-1-one trapped within a
Pavel A Demakov1, Danil N Dybtsev1, Vladimir P Fedin1
1Nikolaev Institute of Inorganic Chemistry, Siberian Branch of the Russian Academy of Sciences, 3 Akad. Lavrentieva Ave., Novosibirsk 630090, Russia. demakov@niic.nsc.ru.
Abstract:
UV-induced [2+2] dimerization of 2-cyclopenten-1-one and 2-methyl-2-cyclopenten-1-one was successfully carried out in a single-crystal-to-single-crystal manner within a porous metal-organic framework. Intermolecular contacts direct the orientation of the α,β-enone molecules within the host channels, which drives the subsequent photoaddition reaction in a facile and diastereoselective fashion, yielding head-to-tail anti dimers only.
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