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Hepatitis E Virus in the Iberian Peninsula: A Systematic Review
Sérgio Santos-Silva1, Danny Franciele da Silva Dias Moraes2, Pedro López-López3,4
1ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal.
Food and Environmental Virology
|July 11, 2023
Summary
Hepatitis E virus (HEV) circulates in humans, animals, and the environment across the Iberian Peninsula. HEV-3 is the most common genotype in people, with recommendations for enhanced surveillance in swine and human diagnostics.
Area of Science:
- Virology
- Public Health
- Epidemiology
Background:
- Hepatitis E virus (HEV) is a significant cause of acute viral hepatitis globally, responsible for millions of infections and thousands of deaths annually.
- HEV infections have been increasingly identified in both human and animal populations within the Iberian Peninsula.
- A comprehensive understanding of HEV epidemiology in this region is crucial for public health interventions.
Conclusions:
- The findings highlight the circulation of diverse HEV genotypes in the Iberian Peninsula, necessitating targeted public health strategies.
- Given Spain's significant pork production and HEV-3's zoonotic potential, implementing HEV surveillance in swine and integrating HEV into human hepatitis diagnostics is recommended.
- Establishing a robust HEV monitoring mechanism is vital for understanding disease prevalence, strain diversity, and public health impact.
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