Related Experiment Video
Updated: Jul 23, 2025
07:12
Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
Published on: January 21, 2020
7.7K
Neuropathic pain in patients with post-COVID-19
Emine Burcu Comruk1, Raikan Buyukavci1, Erol Comruk2
1Department of Physical Medicine and Rehabilitation, Inonu University Faculty of Medicine, Malatya, Türkiye.
Northern Clinics of Istanbul
|July 12, 2023
Summary
Post-COVID-19 patients frequently experience musculoskeletal pain, particularly in the back, low back, and knee. Neuropathic pain occurs in 2.9%-5.7% of cases, influenced by acute COVID-19 severity.
Area of Science:
- Pain Medicine
- Infectious Diseases
- Neurology
Background:
- Persistent musculoskeletal pain is a common sequela following COVID-19 infection.
- Neuropathic pain, characterized by specific symptoms and signs, may also persist post-infection.
Purpose of the Study:
- To investigate the prevalence of continuing pain in the post-COVID-19 period.
- To determine the frequency of neuropathic pain among these patients.
- To identify factors associated with the occurrence of neuropathic pain.
Main Methods:
- 209 participants (18-75 years) with confirmed COVID-19 were assessed.
- Musculoskeletal pain evaluated using the Visual Analog Scale (VAS) and extended Nordic musculoskeletal system questionnaire (NMQ-E).
- Neuropathic pain assessed via the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) and Pain-DETECT (PDQ) questionnaires.
Main Results:
- Musculoskeletal pain most prevalent in the back (20.1%), low back (15.3%), and knee (11.5%).
- Neuropathic pain incidence was 2.9% (LANSS) and 5.7% (PDQ).
- Low back and knee pain significantly correlated with neuropathic pain; acute COVID-19 severity (VAS score) associated with neuropathic pain.
Conclusions:
- Musculoskeletal pain, especially in the back, low back, and knee, is common post-COVID-19.
- Neuropathic pain affects a notable percentage of post-COVID-19 patients (2.9%-5.7%).
- Neuropathic pain should be considered in the ongoing management of patients recovering from COVID-19.
Related Concept Videos
01:44Nociception
28.0K
Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
28.0K
01:23Peripheral Artery Disease V: Postoperative Nursing Management
12
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
12
01:25Analgesia and Pain Management
665
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
665
01:21Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
323
Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
Two synthetic agonists of THC,...
323
01:24Local Anesthetics: Differential Sensitivity of Nerve Fibers
873
Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
873
01:20Pain
508
Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
508