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Updated: Jul 23, 2025

Method to Visualize and Analyze Membrane Interacting Proteins by Transmission Electron Microscopy
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The Amphipathic Helix in Visual Cycle Proteins: A Review

Sheetal Uppal1, Eugenia Poliakov1, Susan Gentleman1

  • 1Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.

Advances in Experimental Medicine and Biology
|July 13, 2023
PubMed
Summary

Researchers found amphipathic helices in retinal pigment epithelial (RPE) proteins. These structures help visual cycle proteins associate with membranes, clarifying their function in vision.

Keywords:
Alpha (α)-helixAmphipathic helixCRALBPLRATMembrane associationRDH5RPE65RetinoidsVisual cycle proteins

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