Related Experiment Video
Updated: Jul 23, 2025
06:52
Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
Published on: September 30, 2020
9.8K
Timing of cognitive effects on afterdischarge termination
Ronald P Lesser1, W R S Webber2, Diana L Miglioretti3
1Department of Neurology Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.
Summary
Cognitive tasks influence brain wave coherence during afterdischarge termination in epilepsy patients. Attention plays a key role in these changes, impacting seizure resolution.
Area of Science:
- Neuroscience
- Epileptology
- Cognitive Science
Background:
- Previous research linked diffuse wavelet cross-coherence changes on electrocorticography (ECoG) to effective afterdischarge termination during cognitive tasks.
- Understanding the temporal dynamics of these coherence changes is crucial for refining therapeutic strategies.
Purpose of the Study:
- To investigate wavelet cross-coherence patterns during distinct time segments of cognitive tasks associated with afterdischarge termination.
- To differentiate the influence of task engagement from seizure resolution on brain wave coherence.
Main Methods:
- Analyzed ECoG data from 12 patients with subdural electrodes undergoing cortical stimulation.
- Compared wavelet cross-coherence across 1-second intervals representing task presentation, patient response, and afterdischarge termination.
Main Results:
- Progressive decreases in coherence were observed over time in the 16.89, 22.53, and 30.03 Hz frequency bands.
- Coherence increased significantly during afterdischarge termination across these bands.
- The 7.13 Hz frequency band exhibited an initial increase followed by a decrease in coherence.
Conclusions:
- Findings suggest that cumulative, non-specific factors like attention modulate coherence throughout cognitive tasks.
- A distinct effect related to the resolution of afterdischarges was identified at the end of the task.
- These results highlight the interplay between cognitive engagement and seizure dynamics.
More Related Videos
Related Concept Videos
01:31Discharge Summary Forms
784
The discharge summary is crucial as it enables a smooth transition from a healthcare facility to a patient's home or another care setting. This critical document facilitates seamless continuity of care, ensuring patients receive the necessary support and attention.
Here's a detailed look at the key components and guidelines for preparing a discharge summary:
Here's a detailed look at the key components and guidelines for preparing a discharge summary:
784
01:30Cognitive Development During Adulthood
160
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
160
01:16Interference and Decay
172
Forgetting is a complex cognitive phenomenon influenced by several factors, among which interference and decay are particularly prominent. These processes explain why individuals often struggle to retrieve specific information from memory, leading to lapses in recall that can be observed in everyday situations.
Interference occurs when competing memories hinder the retrieval of particular information. It can be classified into two types: proactive and retroactive interference. Proactive...
Interference occurs when competing memories hinder the retrieval of particular information. It can be classified into two types: proactive and retroactive interference. Proactive...
172
01:30Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
159
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
159