Racial/Ethnic Patterns in Opioid Dispensing among Medicaid-Funded Young Children

Laksika B Sivaraj1,2, Khoa Truong1, William T Basco3

  • 1Department of Public Health Sciences, Clemson University, Clemson, SC 29634, USA.

PubMed

Insights

Racial disparities exist in pediatric opioid prescriptions for respiratory and injury conditions. White children received more respiratory opioid prescriptions, while Hispanic children received more injury opioid prescriptions, with differences widening over time.

Area of Science:

  • Pediatric pharmacology
  • Health disparities research
  • Public health policy

Background:

  • Opioid prescribing patterns in children require examination, particularly concerning racial and ethnic variations.
  • Understanding these disparities is crucial for equitable healthcare delivery.

Purpose of the Study:

  • To investigate racial/ethnic differences in outpatient opioid dispensing for respiratory system (RESP) and injury (INJURY) diagnoses among children aged 3 years or younger.
  • To analyze trends in these dispensing rates over three distinct three-year periods.

Main Methods:

  • Analysis of South Carolina Medicaid outpatient claims data for children aged 3 years or younger.
  • Calculation of triennial rates of dispensed opioid prescriptions per 1000 visits for RESP and INJURY diagnoses, stratified by racial/ethnic groups.

Main Results:

  • Opioid dispensing rates for RESP conditions decreased across all racial/ethnic groups. White children consistently had higher rates than Black and Hispanic children.
  • Opioid dispensing rates for INJURY conditions also declined overall. Hispanic children showed the highest dispensing rates, followed by White children. The disparity in INJURY prescribing widened over time, with Hispanic children increasingly receiving more prescriptions compared to White and Black children.

Conclusions:

  • Significant racial/ethnic disparities persist in pediatric opioid prescribing for both respiratory and injury-related outpatient visits.
  • These differences, particularly for injury indications, have widened over the study period, highlighting a critical area for intervention to ensure equitable care.

Related Concept Videos

Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
778
Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.0K
Opioid Analgesics: Morphine and Other Natural Cogeners01:20

Opioid Analgesics: Morphine and Other Natural Cogeners

Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
300
Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
343
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents01:17

Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents

Diarrhea, a condition marked by frequent loose or watery bowel movements, can be triggered by multiple factors such as viral or bacterial infections, food intolerances, anxiety, medications, and digestive disorders. Symptoms may include abdominal pain, bloating, nausea, and cramping. Severe or prolonged diarrhea can lead to complications like electrolyte imbalances, malnutrition, and dehydration if left untreated.
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
247
Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
394