Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Carbohydrate Metabolism01:19

Overview of Carbohydrate Metabolism

1.2K
Carbohydrate metabolism is a fundamental biochemical process that ensures a constant supply of energy to living cells. The most important carbohydrate is glucose, which can be broken down via glycolysis to enter into the Krebs cycle and eventually lead to the production of ATP through oxidative phosphorylation.
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
1.2K
Inborn Errors of Metabolism01:20

Inborn Errors of Metabolism

203
Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
203
Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

1.8K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
1.8K
Other Glycolytic Pathways01:24

Other Glycolytic Pathways

49
The pentose phosphate pathway (PPP) operates in parallel with glycolysis, facilitating the metabolism of both pentoses and glucose. This pathway consists of two distinct phases: the oxidative and non-oxidative phases. While it does not directly generate ATP, the intermediates formed during the process can integrate into glycolysis, contributing to cellular energy metabolism when required.Oxidative Phase: NADPH ProductionThe oxidative phase of the pentose phosphate pathway is primarily...
49
Overview of Protein Metabolism01:21

Overview of Protein Metabolism

1.3K
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
1.3K
Regulation of Metabolism01:19

Regulation of Metabolism

9.5K
Cellular needs and conditions vary from cell to cell and change within individual cells over time. For example, the required enzymes and energetic demands of stomach cells are different from those of fat storage cells, skin cells, blood cells, and nerve cells. Furthermore, a digestive cell works much harder to process and break down nutrients during the time that closely follows a meal compared with many hours after a meal. As these cellular demands and conditions vary, so do the amounts and...
9.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cell Membrane Capacitance and Characteristic Frequency Among Youth and Adults: Reference Data From NHANES 1999-2000.

Journal of the American Nutrition Association·2026
Same author

Hamstrings-to-quadriceps ratio in female and male children and adolescents across the velocity spectrum.

European journal of applied physiology·2026
Same author

Reliability and Diurnal-Fatigability Effects on Force-Time Characteristics During Maximal Voluntary Handgrip Contractions.

Motor control·2026
Same author

Muscle Hypertrophy, Strength, and Salivary Hormone Changes Following 9 Weeks of High- or Low-Load Resistance Training.

Journal of functional morphology and kinesiology·2026
Same author

Reliability of achieving target dehydration levels using a portable infrared sauna protocol in healthy young adults.

Journal of the International Society of Sports Nutrition·2025
Same author

Describing Dietary Habits and Body Composition Among High-Intensity Functional Training Athletes: A Mixed Methods Approach.

Sports (Basel, Switzerland)·2025

Related Experiment Video

Updated: Jul 23, 2025

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
09:40

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle

Published on: January 19, 2017

11.8K

Metabolic Flexibility and Inflexibility: Pathology Underlying Metabolism Dysfunction.

Marni E Shoemaker1, Zachary M Gillen2, David H Fukuda3

  • 1School of Health and Consumer Sciences, South Dakota State University, Brookings, SD 57007, USA.

Journal of Clinical Medicine
|July 14, 2023
PubMed
Summary

Metabolic flexibility is skeletal muscle's ability to switch fuel sources. This study explores how this crucial function impacts overall metabolic health and disease prevention.

Area of Science:

  • Exercise Physiology
  • Metabolic Regulation
  • Skeletal Muscle Biology

Background:

  • Metabolic flexibility is key for maintaining energy homeostasis.

More Related Videos

Assessing Energy Substrate Oxidation In Vitro with 14CO2 Trapping
09:20

Assessing Energy Substrate Oxidation In Vitro with 14CO2 Trapping

Published on: March 23, 2022

2.2K
Author Spotlight: Unveiling Mitochondrial Function and Cellular Metabolic Adaptation in Metabolic Diseases
08:12

Author Spotlight: Unveiling Mitochondrial Function and Cellular Metabolic Adaptation in Metabolic Diseases

Published on: October 4, 2024

1.7K

Related Experiment Videos

Last Updated: Jul 23, 2025

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
09:40

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle

Published on: January 19, 2017

11.8K
Assessing Energy Substrate Oxidation In Vitro with 14CO2 Trapping
09:20

Assessing Energy Substrate Oxidation In Vitro with 14CO2 Trapping

Published on: March 23, 2022

2.2K
Author Spotlight: Unveiling Mitochondrial Function and Cellular Metabolic Adaptation in Metabolic Diseases
08:12

Author Spotlight: Unveiling Mitochondrial Function and Cellular Metabolic Adaptation in Metabolic Diseases

Published on: October 4, 2024

1.7K
  • Dysfunctional metabolic flexibility is linked to metabolic diseases like type 2 diabetes.
  • Skeletal muscle plays a central role in substrate utilization and energy balance.