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Development of Antibiotic Resistance01:30

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Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
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Antimicrobial Resistance (AMR).

Ka Wah Kelly Tang1, Beverley C Millar1,2, John E Moore1,2

  • 1School of Biomedical Sciences, Ulster University, Coleraine, United Kingdom.

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|July 14, 2023
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Summary

Antimicrobial resistance (AMR) is a growing global health crisis. Addressing this requires international strategies, the One Health Approach, and increased public awareness to preserve effective treatments for humans and animals.

Keywords:
AMRantibiotic resistanceantimicrobial resistanceinfectionone health

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Area of Science:

  • Public Health
  • Infectious Diseases
  • Global Health Security

Background:

  • Antimicrobial resistance (AMR) is a critical global health issue, projected to cause 10 million deaths annually by 2050.
  • AMR occurs when pathogens no longer respond to antimicrobial treatments, leading to treatment failures in humans and animals.
  • The overuse and misuse of antimicrobials, especially antibiotics, are primary drivers of the escalating AMR crisis.

Purpose of the Study:

  • To review current international strategies addressing antibiotic resistance, including the UN Sustainable Development Goals (SDGs).
  • To examine the role of the One Health Approach in combating AMR by integrating human, animal, and environmental health efforts.
  • To highlight the necessity of enhancing public awareness and health literacy in global and local action plans against AMR.

Main Methods:

  • Review of strategies implemented by international governmental organizations.
  • Analysis of the 'One Health Approach' framework.
  • Assessment of the impact of public awareness and health literacy initiatives.

Main Results:

  • International strategies, including the SDGs, are being employed to combat antibiotic resistance.
  • The One Health Approach offers a multidisciplinary framework for addressing AMR.
  • There is a recognized need to improve public awareness and health literacy regarding AMR.

Conclusions:

  • Antimicrobial resistance is a complex 21st-century public health challenge with profound consequences if unaddressed.
  • A multifaceted approach involving individuals, communities, and nations is essential for preserving effective antimicrobials.
  • Sustained global collaboration is crucial to ensure the future availability of treatments for human and animal health.