Related Experiment Video
Updated: Jul 23, 2025
08:25
Mass Cytometry Analysis of Systemic and Local Immune Responses in Hepatocellular Carcinoma
Published on: April 25, 2025
239
Liquid Biopsy in Hepatocellular Carcinoma
Zheyu Zhou1,2, Xiaoliang Xu2,3, Yang Liu3
1Department of General Surgery, Nanjing Drum Tower Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Graduate School of Peking Union Medical College, Nanjing, China.
Methods in Molecular Biology (Clifton, N.J.)
|July 14, 2023
Summary
Liquid biopsy shows promise for diagnosing and monitoring hepatocellular carcinoma (HCC), offering a potential improvement over traditional methods like alpha-fetoprotein tests or liver biopsies for early detection and prognosis.
Area of Science:
- Oncology
- Hepatology
- Molecular Diagnostics
Background:
- Hepatocellular carcinoma (HCC) is a highly lethal cancer with a poor prognosis.
- Current diagnostic and prognostic tools, including alpha-fetoprotein (AFP) and liver biopsy, are insufficient due to tumor heterogeneity.
- There is a critical need for improved methods for early diagnosis and prognosis of HCC.
Conclusions:
- Liquid biopsy represents a promising advancement in managing hepatocellular carcinoma.
- Its non-invasive nature and real-time monitoring capabilities address limitations of current diagnostic tools.
- Further research and clinical integration of liquid biopsy are expected to enhance HCC patient outcomes.
