Related Experiment Video
Updated: Jul 23, 2025

Dispersion of Nanomaterials in Aqueous Media: Towards Protocol Optimization
Published on: December 25, 2017
The treatment of dispersion terms for solution systems
De-Cai Fang1, Si-Cong Liu1, Dan-Yang Liu1
1College of Chemistry, Beijing Normal University, Beijing 100875, P. R. China. dcfang@bnu.edu.cn.
Abstract:
DFT calculations of reaction mechanisms in solution have always been a hot topic, especially for transition-metal-catalyzed reactions, in which the traditional DFT-D3 method has been extensively employed. The overestimation of the dispersion from the traditional DFT-D3 method leads to a quite low activation free-energy barrier, so it is worth finding a proper way to deal with the dispersion for solution systems. The solvent-solute dispersion is also important for solution systems, and thus it should be calculated together with the solute dispersion. The newly generated solute-solute dispersion energy should be shared equally with the newly formed cavity between two interacting species; therefore, only half of the solute-solute and solvent-solute dispersion terms belong to the solute molecule. The detailed treatment of dispersion correction for solution systems has been fully addressed, and this method has been confirmed with the examples of ligand exchange reactions and catalytic reactions.
Related Concept Videos
Van der Waals Interactions
Distribution and Dispersion
Colloidal precipitates
Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model
Solution Formation
This selective...
Colloids

