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Updated: Jul 23, 2025

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
MRI findings in movement disorders and associated sleep disturbances
Sadegh Ghaderi1, Asra Karami2, Azadeh Ghalyanchi-Langeroudi3,4
1Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences Tehran, Iran.
Background:
One of the most useful tools for identifying sleep disturbances is neuroimaging, especially magnetic resonance imaging (MRI). This review research was to look at the role of MRI findings in movement disorders and sleep disturbances.
Methods:
This review collects all MRI data on movement disorders and sleep disruptions. Between 2000 and 2022, PubMed and Google Scholar were utilized to find original English publications and reviews. According to the inclusion and exclusion criteria, around 100 publications were included. We only looked at research that explored MRI modality together with movement problems, sleep disorders, and brain area involvement. Most of the information focuses on movement irregularities and sleep interruptions.
Results:
Movement disorders such as Parkinson's disease (PD), Huntington's disease (HD), neuromuscular diseases, rapid eye movement (REM) sleep behavior movement disorder (RBD), cerebellar movement disorders, and brainstem movement disorders are assessed using MRI-based neuroimaging techniques. Some of the brain areas were associated with disorders in movement abnormalities and related sleep disturbances. This review found that many people with mobility disorders also have sleep problems. Some brain areas' malfunctions may cause motor and sleep issues.
Conclusion:
Neuroimaging helps us understand the sleep difficulties associated with movement disorders by examining the structural and functional implications of movement disorders and sleep disturbances.
Insights
Magnetic resonance imaging (MRI) reveals connections between movement disorders and sleep disturbances. Neuroimaging highlights how brain area malfunctions contribute to both motor and sleep issues, aiding diagnosis and understanding.
Area of Science:
- Neurology
- Neuroimaging
- Sleep Medicine
Background:
- Neuroimaging, particularly magnetic resonance imaging (MRI), is crucial for identifying sleep disturbances.
- Movement disorders often present with associated sleep disruptions, necessitating advanced diagnostic tools.
Purpose of the Study:
- To review the role of magnetic resonance imaging (MRI) findings in understanding movement disorders and their associated sleep disturbances.
- To synthesize current research on the neuroimaging of motor and sleep abnormalities.
Main Methods:
- Systematic literature review of MRI studies on movement disorders and sleep disruptions.
- Searched PubMed and Google Scholar (2000-2022) for English publications, including original research and reviews.
- Included approximately 100 publications focusing on MRI, movement disorders, sleep disorders, and brain region involvement.
Main Results:
- MRI techniques assess movement disorders like Parkinson's disease (PD), Huntington's disease (HD), and REM sleep behavior disorder (RBD).
- Specific brain areas are linked to movement abnormalities and related sleep disturbances.
- A significant overlap exists between mobility disorders and sleep problems, suggesting common underlying neurological causes.
Conclusions:
- Neuroimaging provides critical insights into the structural and functional correlates of sleep difficulties in movement disorders.
- Understanding the brain basis of these comorbidities aids in diagnosis and therapeutic strategies.
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