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Published on: November 10, 2014
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Understanding droplet jetting on varying substrate for biological applications
Jia Min Lee1, Xi Huang1, Guo Liang Goh2
1HP-NTU Digital Manufacturing Corp Lab, School of Mechanical & Aerospace Engineering, Nanyang Technological University, Singapore.
International Journal of Bioprinting
|July 17, 2023
Summary
This review explores inkjet printing physics, focusing on droplet jetting and impact on various materials. Optimizing these processes enhances cell viability and enables applications like drug screening.
Area of Science:
- Biotechnology
- Materials Science
- Fluid Dynamics
Background:
- Inkjet printing involves distinct jetting and impact phases.
- Understanding droplet behavior on diverse substrates (solid, liquid, viscoelastic) is crucial.
Purpose of the Study:
- To review the physics governing inkjet printing, from droplet formation to impact.
- To highlight strategies for improving cell viability and construct integrity in inkjet bioprinting.
Main Methods:
- Analysis of droplet formation and jetting dynamics.
- Investigation of droplet impact physics on different material types.
- Review of techniques to mitigate cell deformation and modify post-impact events.
Main Results:
- Optimizing jetting and impact phases improves cell viability.
- Post-impact modifications (spreading, evaporation, absorption) enhance cell survival.
- Inkjet bioprinting integration with other technologies boosts structural integrity and biofunctionality.
Conclusions:
- Inkjet bioprinting requires understanding droplet physics for successful construct fabrication.
- Process optimization is key to improving cell viability and enabling advanced applications.

