Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Relation between Poisson's ratio, Modulus of Elasticity and Modulus of Rigidity01:15

Relation between Poisson's ratio, Modulus of Elasticity and Modulus of Rigidity

296
Deformation occurs in axial and transverse directions when an axial load is applied to a slender bar. This deformation impacts the cubic element within the bar, transforming it into either a rectangular parallelepiped or a rhombus, contingent on its orientation. This transformation process induces shearing strain. Axial loading elicits both shearing and normal strains. Applying an axial load instigates equal normal and shearing stresses on elements oriented at a 45° angle to the load axis.
296
Residual Stresses in Bending01:18

Residual Stresses in Bending

211
In the study of elastoplastic members subjected to bending moments, understanding the loading and unloading phases is crucial for assessing material behavior and structural integrity. During the loading phase, as the bending moment increases, the material initially responds elastically, adhering to Hooke's Law, where stress is directly proportional to strain. When the load exceeds the yield strength, plastic deformation occurs, resulting in permanent strain and deformation that remains even...
211
Hooke's Law01:26

Hooke's Law

481
Hooke's law, a pivotal principle in material science, establishes that the strain a material undergoes is directly proportional to the applied stress, defined by a factor called the modulus of elasticity or Young's modulus.
481
Cell-matrix's Response to Mechanical Forces01:13

Cell-matrix's Response to Mechanical Forces

2.7K
In animal cells, the extracellular matrix allows cells within tissues to withstand external stresses and transmits signals from the outside of the cell to the inside. The extracellular matrix is extensive, and its composition varies between different types of tissues. For example, the reticular fibers and ground substance make up the ECM in loose connective tissue, while collagen and bone minerals make up the ECM of bone tissue. 
Anchoring junctions mechanically attach a cell to the...
2.7K
Transformation of Plane Strain01:12

Transformation of Plane Strain

196
When analyzing elongated structures like bars subjected to uniformly distributed loads, it is essential to understand the transformation of plane strain when coordinate axes are rotated. This transformation helps to assess how material deformation characteristics vary with orientation, which is crucial in materials science and structural engineering.
Under plane strain conditions, typical for members where one dimension significantly exceeds the others, deformations and resultant strains are...
196
Members Made of Elastoplastic Material01:19

Members Made of Elastoplastic Material

125
The behavior of elastoplastic materials under bending stresses, particularly in structural members with rectangular cross-sections, is crucial for predicting material responses and understanding failure modes. Initially, when a bending moment is applied, the stress distribution across the section follows Hooke's Law and is linear and elastic. This distribution means the stress increases from the neutral axis to the maximum at the outer fibers, up to the elastic limit.
As the bending moment...
125

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interface Conditions in Phenotype-Structured Models with Basement Membranes and Cell Layers.

Bulletin of mathematical biology·2026
Same author

Two-step global sensitivity analysis of a non-local integro-differential model for Cancer-on-Chip experiments.

Mathematical biosciences·2024
Same author

Selected aspects of avascular tumor growth reproduced by a hybrid model of cell dynamics and chemical kinetics.

Mathematical biosciences·2024
Same author

A non local model for cell migration in response to mechanical stimuli.

Mathematical biosciences·2023
Same author

A phenotype-structured model to reproduce the avascular growth of a tumor and its interaction with the surrounding environment.

Journal of theoretical biology·2021
Same author

A nonlinear elastic description of cell preferential orientations over a stretched substrate.

Biomechanics and modeling in mechanobiology·2021

Related Experiment Video

Updated: Jul 23, 2025

A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology
16:46

A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology

Published on: June 3, 2014

11.8K

Modelling Cell Orientation Under Stretch: The Effect of Substrate Elasticity.

Annachiara Colombi1, Luigi Preziosi2, Marco Scianna1

  • 1Department of Mathematical Sciences "G.L. Lagrange", Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129, Turin, Italy.

Bulletin of Mathematical Biology
|July 17, 2023
PubMed
Summary

Cell orientation on soft substrates switches based on substrate stiffness. Elongated cells favor oblique alignment, while rounder cells align perpendicularly or parallel to stretching.

Failed At:

2026-07-14T07:36:08.473842+00:00

Keywords:
Cell orientationCell–substrate interactionMechanosensing

More Related Videos

Stretching Micropatterned Cells on a PDMS Membrane
09:41

Stretching Micropatterned Cells on a PDMS Membrane

Published on: January 22, 2014

15.4K
Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy
08:46

Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy

Published on: June 13, 2025

265

Related Experiment Videos

Last Updated: Jul 23, 2025

A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology
16:46

A Novel Stretching Platform for Applications in Cell and Tissue Mechanobiology

Published on: June 3, 2014

11.8K
Stretching Micropatterned Cells on a PDMS Membrane
09:41

Stretching Micropatterned Cells on a PDMS Membrane

Published on: January 22, 2014

15.4K
Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy
08:46

Equibiaxial Stretching Device for High Magnification Live-Cell Confocal Fluorescence Microscopy

Published on: June 13, 2025

265