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Multiple primary tumours in laryngeal cancer
The Journal of Laryngology and Otology
|August 1, 1986
Summary
A study of 748 laryngeal cancer patients found 14% developed second primary tumors, primarily lung cancer. This highlights the need for respiratory screening in laryngeal cancer patients.
Area of Science:
- Oncology
- Medical Research
Background:
- Squamous cell carcinoma of the larynx is a significant diagnosis.
- Understanding the risk of secondary primary tumors is crucial for patient management.
Purpose of the Study:
- To retrospectively analyze the incidence of multiple primary tumors in laryngeal cancer patients.
- To identify risk factors and common sites for second primary tumors.
Main Methods:
- Retrospective analysis of 748 laryngeal squamous cell carcinoma patients treated between 1964 and 1983.
- Data collection focused on the occurrence and location of second primary tumors.
Main Results:
- 104 (14%) patients developed second primary tumors.
- 73 (10%) were in the respiratory and upper digestive tracts, with 64 in the lung.
- Male patients with glottic carcinoma had a higher risk (14.5%) than females (0%).
Conclusions:
- The high incidence of lung cancer as a second primary tumor warrants consideration.
- Bronchoscopy is recommended during initial work-up and follow-up for laryngeal cancer patients.