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Published on: December 21, 2019
Chinese expert consensus on the diagnosis and treatment of malignant pleural mesothelioma
Qian Wang1, Chunwei Xu2,3,4, Wenxian Wang3
1Department of Respiratory Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Abstract:
Malignant pleural mesothelioma (MPM) is a malignant tumor originating from the pleura, and its incidence has been increasing in recent years. Due to the insidious onset and strong local invasiveness of MPM, most patients are diagnosed in the late stage and early screening and treatment for high-risk populations are crucial. The treatment of MPM mainly includes surgery, chemotherapy, and radiotherapy. Immunotherapy and electric field therapy have also been applied, leading to further improvements in patient survival. The Mesothelioma Group of the Yangtze River Delta Lung Cancer Cooperation Group (East China LUng caNcer Group, ECLUNG; Youth Committee) developed a national consensus on the clinical diagnosis and treatment of MPM based on existing clinical research evidence and the opinions of national experts. This consensus aims to promote the homogenization and standardization of MPM diagnosis and treatment in China, covering epidemiology, diagnosis, treatment, and follow-up.
Insights
Malignant pleural mesothelioma (MPM) is a growing cancer requiring early detection. A new consensus standardizes MPM diagnosis and treatment for better patient outcomes.
Area of Science:
- Oncology
- Thoracic Surgery
- Pulmonology
Background:
- Malignant pleural mesothelioma (MPM) incidence is rising globally.
- MPM presents insidiously, often diagnosed at late stages, necessitating early screening.
- Current treatments include surgery, chemotherapy, radiotherapy, immunotherapy, and electric field therapy.
Purpose of the Study:
- To establish a national consensus on the clinical diagnosis and treatment of MPM in China.
- To standardize MPM management based on evidence and expert opinion.
- To guide early screening and treatment for high-risk populations.
Main Methods:
- Development of a consensus by the Mesothelioma Group of the Yangtze River Delta Lung Cancer Cooperation Group (East China LUng caNcer Group, ECLUNG; Youth Committee).
- Review of existing clinical research evidence.
- Incorporation of national expert opinions.
Main Results:
- A comprehensive consensus document covering epidemiology, diagnosis, treatment, and follow-up of MPM.
- Recommendations for promoting standardized and homogenized MPM care.
- Emphasis on early detection and tailored treatment strategies.
Conclusions:
- The developed consensus provides a framework for consistent MPM diagnosis and treatment in China.
- Standardization of care is expected to improve patient outcomes and survival rates.
- The consensus addresses the critical need for improved management of this challenging malignancy.
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