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Related Experiment Video

Updated: Jul 23, 2025

Patterning of Microorganisms and Microparticles through Sequential Capillarity-assisted Assembly
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Patterning of Microorganisms and Microparticles through Sequential Capillarity-assisted Assembly

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Modular assembly of microswimmers with liquid compartments.

Minghan Hu1, Xueting Shen1, Daniel Tran1

  • 1Laboratory for Soft Materials and Interfaces, Department of Materials, ETH Zürich, Zürich, Switzerland.

Journal of Physics. Condensed Matter : an Institute of Physics Journal
|July 18, 2023
PubMed
Summary
This summary is machine-generated.

Researchers developed a modular platform for fabricating artificial microswimmers with multiple liquid compartments. This innovation enables precise cargo delivery for applications in medicine and environmental science.

Keywords:
capillary assemblymicrocapsulesmicrofluidicmicroswimmers

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Area of Science:

  • Colloidal science
  • Materials science
  • Microfluidics

Background:

  • Artificial microswimmers are key models for out-of-equilibrium systems.
  • Potential applications include biomedicine and environmental remediation, often involving cargo delivery.
  • Fabricating microswimmers with multiple liquid compartments for efficient cargo loading is challenging.

Purpose of the Study:

  • To present a modular fabrication platform for microswimmers with multiple liquid compartments.
  • To enable precise assembly and programmable functionalities for cargo transport and release.

Main Methods:

  • Utilized microfluidic synthesis for creating polymer-based microcapsules (3-6 μm).
  • Employed sequential capillarity-assisted particle assembly (sCAPA) for precise microcapsule assembly.
  • Integrated microfluidic devices with sCAPA for modular microswimmer fabrication.

Main Results:

  • Successfully synthesized monodisperse microcapsules with diverse liquid cargoes.
  • Assembled microcapsules into versatile microswimmers with multiple liquid compartments using sCAPA.
  • Demonstrated high precision in assembling microswimmers with programmable functionalities.

Conclusions:

  • The developed platform offers a flexible approach for fabricating modular microswimmers.
  • These microswimmers show potential for active cargo transport and on-demand release.
  • This work advances the design and application of artificial microswimmers.