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Network Visualization Analysis on MicroRNAs in Infectious Diseases Research Area.
Sevil Alkan1, Mustafa Serhat Şahinoğlu2, Havva Yasemin Çinpolat3
1Department of Infectious Disease, Faculty of Medicine, Çanakkale Onsekiz Mart University, Çanakkale, Turkey.
Oman Medical Journal
|July 19, 2023
Summary
Bibliometric analysis reveals a surge in microRNA (miRNA) research for infectious diseases since 2019, with China and the USA leading contributions. Key miRNAs like miR-146 and miR-155 are implicated in sepsis and infection, offering new therapeutic avenues.
Area of Science:
- Molecular Biology
- Genetics
- Infectious Diseases
Background:
- MicroRNAs (miRNAs) regulate gene expression post-transcriptionally.
- Existing literature explores the link between miRNAs and viral/bacterial infections.
- A bibliometric evaluation is needed to assess the research landscape of miRNAs in infectious diseases.
Purpose of the Study:
- To conduct a bibliometric evaluation of publications on miRNAs in infectious disease research.
- To identify research trends, significant publications, and collaboration clusters.
- To understand the development and direction of research in this field.
Main Methods:
- Data retrieved from the Web of Science (WoS) database on April 10, 2022.
- Bibliometric analysis of publication data including titles, authors, affiliations, keywords, and citations.
- VOSviewer software used for visualizing country collaboration networks and keyword co-occurrence.
Main Results:
- A total of 623 documents were identified, with a significant increase in publications since 2019.
- China (63.9%) and the USA (16.1%) are the leading countries in scientific production.
- Key deregulated miRNAs such as miR-122, miR-146, and miR-155 were identified in the context of sepsis and infection.
Conclusions:
- Research on miRNAs in infectious diseases has shown a steady increase since 2019.
- China and the USA are major contributors to this research area.
- Identifying key miRNAs and understanding research trends can inform new strategies for managing infections.
