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Numerical Study of a Thrombus Migration Risk in Aneurysm After Coil Embolization in Patient Cases: FSI Modelling
C Paz1, E Suárez2, A Cabarcos2
1CINTECX, Universidade de Vigo, Campus As Lagoas-Marcosende, 36310, Vigo, Spain. cpaz@uvigo.es.
Cardiovascular Engineering and Technology
|July 19, 2023
Summary
Clots near aneurysm walls rarely migrate. However, clots in the center pose a migration risk, impacting aneurysm treatment and patient follow-up. This study models clot migration dynamics.
Area of Science:
- Biomedical Engineering
- Computational Fluid Dynamics
- Medical Physics
Background:
- Modeling thrombus migration in aneurysms presents significant challenges.
- Understanding clot behavior is crucial for post-intervention patient management.
Purpose of the Study:
- To model cerebral aneurysm clot migration in a realistic aneurysm.
- To analyze forces acting on clots within an aneurysm using transient fluid-structure interaction (FSI) simulations.
Main Methods:
- Blood flow modeled with Womersley profile and Carreau viscosity.
- Clots modeled with hyperelastic Ogden model; artery walls with linear elastic model.
- FSI coupled model implemented in ANSYS®; hemodynamic forces quantified for various clot sizes and positions.
Main Results:
- Clots adjacent to aneurysm walls showed minimal risk of migration.
- Clots positioned centrally within the aneurysm presented a significant risk of migration.
- Typical post-coiling intervention clots near the wall had a very low migration risk, even during intense events.
Conclusions:
- The FSI methodology effectively evaluates clot migration risk in aneurysms.
- This approach advances personalized medicine and patient follow-up after endovascular interventions.
- It aids medical teams in optimizing treatment decisions and patient care.
